Ignatov, I., Mosin, O. V. (2013) Structural Mathematical Models
Describing Water Clusters, Journal of Mathematical Theory and Modeling,
Vol. 3, No. 11, pp. 72-87.

Ignatov, I., Mosin, O. V., Velikov, B., Bauer, E. Tyminski, G. (2014) Longevity
Factors and Mountain Water as Factor. Research in Mountain and Fields Areas
in Bulgaria, Civil and Environmental Research, Vol. 30, No. 4, pp. 51-60.

Water in the Human Body is Informational Bearer about Longevity

Prof. Ignat Ignatov,
Dr. Oleg Mosin,
2012, Sofia, Bulgaria; Moscow, Russia

Practical Scientific Project “Nature, Ecology, Longevity”

Entropy and time in living matter
The reasons for aging
Water – the base of life and longevity
Clinical evidence for the health benefits of mountain and defrosted water
Water in human body carries information about longevity
Bibliography

Days of Mountain Water and Healing Tourism 2012 Teteven, Bulgaria
Water and Longevity, Prof. Ignatov, Dr. Mosin
Teteven, Bulgaria, Days of Mountain Water and Healing Tourism
Zoko films

1. Entropy and time in living matter

Mankind has always been excited about longevity. Biophysical studies indicate that the water in the human body “has departed” from the water at the time of origination of life (Semihina, Mosin, Ignatov). The more rapid the life processes are, the faster the states of orderliness are observed, i.e. entropy in the living organism decreases. Yet this leads to difficulties in compensating entropy with the entropy of the environment, which is associated with metabolism and energy. Such organisms, like mammals, can live up to 100 years. In trees the processes are slower, the states of orderliness are harder to obtain, and entropy decreases more slowly than in animals.

Prof. Ignat Ignatov with turtle,
Halkida, Greece, 2010

There are trees that live for more than 1000 years. For example, a turtle’s life processes are slower than those of mammals and faster than those of trees. It can live up to 300 years. We can define a specific time for each living creature, and their time to a certain degree differs from the time of the environment. This time correlates with parameters of the vital activity of living organisms (Ignatov, 2011). Entropy is a measure of randomness or disorder of the physical system. It is expressed in the number of possible arrangements of the components. Prigozhin received the Nobel Prize explaining that at a statistical level the chaotic states of living systems lead to an irreversible behavior. Self-structuring and self-organization are observed. He explains the auto-oscillatory reaction of Belousov–Zhabotinsky. Prigozhin shows how together with the increase of entropy, self-organization originates. According to the author, living organisms decrease their own entropy due to their orderliness. This orderliness increases with the transition from unicellular to multicellular organisms. Cells divide in a particular sequence.

In the 19th century the French scientist Brillouin defined entropy in information systems. On the grounds of biophysical information flows from the living creatures to the environment and vice versa, information properties and the entropy of water in living organisms are changed (Ignatov, Antonov, 1998). Biophysical parameters are introduced for a change of the average energy of the hydrogen bonds in water. “Informatiоnability” of water is related to decrease of entropy in the restructuring of water molecules as a result of external influence (Ignatov, Antonov, 1998). In 2009 the Russian scientist Dulnev measured the parameters of chaos and order as parameters of entropy for one component in a living organism. Yet the living cell is multi-parameter with regard to biophysical parameters (Ignatov, 2011).

2. The reasons for aging

Aging is associated with accumulation of errors in DNA replication. The free radicals have an adverse affect on this process. Deuterium atoms in water molecules and radiation also have an adverse effect on DNA replication in the human organism. Aging is a non-linear process. The rate of aging increases with time. In 1963 Orgel demonstrated that the aging process is associated with the synthesis of proteins. The accumulation of errors in protein synthesis increases exponentially with age.

Probable dependence between accumulated
DNA errors and cancer mortality
(Orgel, 1963, Goodall, 2003)

Cells taken from adults show reduced transcription or transmission of information from DNA to RNA. Therefore the likelihood of cancer increases with age.

Deuterium is a heavier isotope of hydrogen. It hinders vital processes in living organisms (Mosin, 1996). This isotope of hydrogen affects the process of mitosis (Dr. Lamprecht, Dr. Schroeter, Dr. Paweletz, 1989). This is an even distribution of genetic material from a mother cell to two daughter cells. Deuterium induces physiological, morphological and cytological changes in the cell. It is estimated that in his lifetime a man takes up 12-15 kg of deuterium.

The study of the water spectrum in the human body can also answer the question of longevity.

3. Water – the base of life and longevity

When considering the question of longevity, one has to analyze which are the areas inhabited by the largest number of long-lived people and what are the reasons for that.

Hydrogen, Deuterium –
Isotope of hydrogen

In the process of development of each organism, water plays an important part – fundamental matrix of life with a structure, isotope composition and ability to store and transmit information. The human body consists 50-75% of water depending on the age and gender. Water is part of the composition of the organism’s physiological liquids and plays the role of an internal medium where vital biochemical processes function with the participation of ferments. Because of this, water carries information in the organism regarding aging and longevity.

Human experience shows that long-living people inhabit mainly high mountain areas. In the Russian North there are a lot more centenarians compared to other parts of Russia. One explanation for this is that the water there contains less deuterium molecules (Berdishev, 1960).

From 1960 to 1965 the scientist Berdishev from the Tomsk Medical Institute studied centenarians in Yakutia and Altai. He linked the longevity of the Yakuts and the Altaians with the use of water from glaciers formed earlier than the Greenland ones. It is well known that most of the Russian centenarians live in Dagestan and Yakutia – 353 and 324 persons per million inhabitants. This figure for Russia is only 8 people. According to Berdishev, defrosted water has a beneficial effect on cellular metabolism. Besides, these people as well as the Buryats, drink mountain water obtained after the melting of ice. The temperature of this water is 10-15 oC. Berdishev assumed that it contained a smaller amount of deuterium.

The report's authors consider the possibility of extending human life and reducing errors in transcription and replication of DNA in the synthesis of proteins depending on the water we drink. Analyses of water on the planet show that mountain water contains the smallest amounts of deuterium atoms in water molecules. In winter and early spring deuterium content is reduced.

"Diffused" ice structures
in defrosted water

According to isotopic composition, defrosted water can be regarded as water deuterium-depleted water or "light" water. Cold mountain water has crystal-like structure and consists of water clusters. With the melting of ice only 15% of hydrogen bonds are destroyed. In this way mountain water contains ice microcrystals. It is quite possible that for this reason defrosted water is beneficial for the body and improves the permeability of cell membranes

4. Clinical evidence for the health benefits of mountain and defrosted water

Experiments with plants and animals have shown that when using water containing 25-30% less deuterium atoms, pigs, rats and mice have an offspring that is bigger and more numerous. Birds that drink deuterium depleted water have accelerated development of their sexual organs and their spermatogenesis process is quickened, laying eggs increases almost 2 times. Wheat matures earlier and gives a richer harvest.

The water molecules in which the hydrogen atoms are of the deuterium isotope have difficulty passing through the cell membrane. Marinov reports rapid growth of flowers in Siberia. In the 1970s, together with Russian scientists, he proved that the water in the region contained less deuterium.

5. Water in human body carries information about longevity

Studies were performed on a 1% solution of blood serum with the method of spectral analysis of a non-equilibrium energy spectrum (NES) Antonov© (1983) and differential non-equilibrium energy spectrum (DNES), Antonov© (1993), Ignatov © (1998). Empirical blood serum samples were provided by Kalinka Naneva, Municipal Hospital, Teteven, Bulgaria. The samples were divided into 2 groups of people between 50 and 70 years of age. The first group consisted of people in excellent health. The second group consisted of people in a critical state and suffering from malignant tumors. The average energy of hydrogen bonds among water molecules in the blood serum was examined as a biophysical parameter. The result was obtained as a difference between the spectrum of 1% solution of blood serum (NES) and a control sample with deionized water (NES). This spectrum is DNES. The first group obtained the result – -9.1±1,1 meV, and the second – -1.6±1,1 meV. There is statistical difference between the two groups of results according to the t-criterion of Student at level p <0,05.

Water in the human body has a spectrum for the life like information bearer. For the control group of healthy people the value of the spectrum of the largest local maximum is at -0.1387 eV or at a wavelength of 8.95 μm.

For the group of people in a critical state and the patients with malignant tumors, the values of the spectrum of the largest local maximums shift to lower energies compared with the control group.

Differential non-equilibrium energy spectrum, DNES,
deionized water (Antonov, 1993)

A study of blood serum was performed by the method of infrared spectral analysis (Krasnov, Gordetsov, 2009). The following peaks in the spectrum of absorption were received - 8.55, 8.58, 8.70, 8.77, 8.85, 9.10, 9.35 and 9.76 μm. The resulting peak at 8.95 (Ignatov, 2012) is close to the one obtained by Russian scientists at 8.85 μm. In the control group of healthy people, the function of distribution according to energy f(E) at 8.95 μm has an average value of 75.3 reciprocal eV (еV^-1). In the group of people in critical condition this value is 24.1 reciprocal eV. The confidence level of the obtained results is p <0.05 by the t-criterion.

In 1992 Antonov performed experiments with the impact on tumor cells of a mouse in water. There was a decrease of the spectrum compared with the control sample of cells from a healthy mouse. Decrease was also observed in the spectrum of the blood serum of terminally ill people to that of healthy people. With the age increase of long-living blood relatives, the function of distribution according to energies at -0.1387 eV decreases. With this group a result was obtained at DNES – -5.5±1,1 meV at an age difference of 20-25 years compared with the control group.

Most of the long-living people in Bulgaria inhabit the Rhodope Mountains. One of the mountain waters, which have a spectrum similar to the spectrum of healthy people blood serum in 8.95 μm, is the water in the Rhodopes. The mountain waters from Teteven, Boyana, etc., have similar parameters.

Nobel laureate Montagnier, Aissa, Del Giudice and co-authors researched the transfer of information from an aqueous solution of DNA molecules to water. An electromagnetic field with a frequency of 7 Hz was applied. Information about DNA is obtained in water. According to the co-authors, information about longevity can be reflected by the genome of centenarians in the water spectrum. The structure of water in the human body also affects the length of human life and is associated with it. Studies of blood serum with the DNES method show that with an analysis of the average energy, the hydrogen bonds and the function of distribution according to energies, one can analyze the vital status of man and the life expectancy associated with it. Water in the human body has spectrum carrying information about life. The influence of the deuterium atoms in water on the human body is rather on the spectrum and thence on the vital functions (Ignatov, Mosin, 2012).

The human organism spends nine months in the aquatic environment in the mother’s womb. During this stage the body contains the largest quantity of water. It is quite possible that there is a correlation to the content of deuterium, and the spectrum of blood serum in the mother’s organism (Dr. Ignatov, Dr. Mosin).

At this stage in the development of civilization stress has an impact on life expectancy. Russian scientists Semihina and Krisheniuk have results of alterations in the water spectrum in the presence of stress (Semihina, Krisheniuk, 2005).