Prof. Dr. Ignat Ignatov - Curriculum Vitae - Scientific Research Center of Medical Biophysics (SRCMB)

Microbiological Research of the Effects of EVODROP Silver Nanoparticle on Escherichia coli, Enterococci and Coliforms

Nedyalka Valcheva, Ignat Ignatov, Fabio Huether

Abstract


The aim of the study was to analyze the microbiological effects of EVODROP Silver Nanoparticle. A comparative analysеs of the number of bacteria of a given species before and after influence wеre performed.

Nanoparticle Silver makes physical changes in the bacterial membrane, like the membrane damage, which can lead to cellular contents leakage and bacterial death [1,2,3]. There are effects of Nanoparticle Silver against SARS-CoV-2. The coronavirus gets replicated via copying of the genetic material using the enzyme RNA-dependent RNA polymerase [4,5].

The membranes of the cells of mammals don’t have peptidoglycans and Ag+ has not inhibiting effect [6]. In such a way it prevents the further alteration of the enzymes.

In Japanese study there are proofs that Nanoparticle Silver inhibiting extracellular SARS-CoV-2 at concentrations ranging between 1 and 10 ppm while cytotoxic effect was observed at concentrations of 20 ppm and above [7]. There is objective research of the effects of Nanoparticle Silver on the virus SARS-CoV-2 with Inhalation in Israel [8].

The author of the device EVOhygiene Fabio Huether performs liquid with concentration 20 ppm nano silver and size of nano particles 5 nm.

The virucidal activity of silver nanoparticles (AgNPs) allows its wider application in the annihilation or amelioration of several viral infections such as Poliovirus type-1, Coxsackievirus B3, influenza A virus, SARS-CoV-2 etc. [9]

There is publication in Nature Nanotechnology for the effects of Silver Nanoparticles as disinfectant against SARS-CoV-2 [10].

Keywords:EVODROP silver nanoparticle, water with bacteria, Escherichia coli, enterococci, coliforms microbiological indicators


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